Birth defects in penis caused by estrogen

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Updated February 15, In prenatal ultrasounds or at delivery, many new parents look between their baby's legs: the presence of a penis is taken as a strong sign that it's a boy. For humans and other animals, development of a penis was thought to be driven by "male hormones" androgens produced entirely by the testes of the male fetus as it grows in the uterus.

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Learn about the various genital abnormalities that can arise in a developing fetus during pregnancy. Answers from Canadian Paediatric Hospitals. Some babies are born with congenital abnormalities, or birth defects, in their genital tract.

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Hypospadias is a birth defect where the urethra is located on the underside of the penis, instead of the tip of the penis. Since the urethra carries urine and semen out of the penis, this causes problems for urinating and intercourse. The birth defect affects about five out of every 1, boys born in the United States having the penile defect.

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Babies born to women with a diet high in certain plant compounds may have lower risks of a birth defect of the penis, according to a new study. The study researchers found that higher intakes of plant estrogens primarily found in flax seeds, soy products, whole grain cereals and some vegetables were associated with reduced risks of delivering infants with hypospadiasa condition in which the urethral opening is on the underside of the penis. Scientists have suspected that a mother's diet high in estrogens derived from plants, for example, in vegetarian womenmay be related to the condition, by having an impact on the developing fetus' hormones. However, it wasn't clear whether this impact would be negative or positive.

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Hypospadias is a condition in which the opening of the urethra is on the underside of the penis instead of at the tip. The location of the opening can vary and can be anywhere from underneath the tip of the penis more common to the base of the penis less common. Hypospadias hi-poe-SPAY-dee-us is a birth defect congenital condition in which the opening of the urethra is on the underside of the penis instead of at the tip.

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Author contributions: Z. Congenital penile anomalies CPAs encompass a range of malformations, including failure of urethral tube closure hypospadiaspenile curvature chordeemicropenis, and feminization of male genitalia. Both genetic anomalies and exposures to endocrine disrupting chemicals EDCs are suspected to be involved; however, little is known about the underlying causes or the developmental window s of sensitivity to antiandrogenic or estrogenic signals.

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Hypospadias pronounced hype-oh-spay-dee-us is a birth defect in boys where the opening of the urethra the tube that carries urine from the bladder to the outside of the body is not located at the tip of the penis. Click here to view a larger image. Hypospadias is a birth defect in boys in which the opening of the urethra is not located at the tip of the penis.

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Baylor College of Medicine scientists defined a previously unrecognized genetic cause for two types of birth defects found in newborn boys, described in a report published in the journal Nature Medicine. Dolores Lamb, director of the Center for Reproductive Medicine at Baylor, professor and vice chair for research of urology and molecular and cellular biology at Baylor and lead author of the report. Cryptorchidism is characterized by the failure of descent of one or both testes into the scrotum during fetal development.

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Penile torsion is a fairly common congenital present from birth condition that can affect any male infant. It occurs more commonly than previously thought, even perhaps up to about 1 in 80 newborn males. It can range from mild to severe.

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